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Risk of bias evaluation for included cohort research Study Belva, 2011259 N N U N N N N N Y U Y N N Bodri, 2008268 N Y U N N U U Y N Y U Y Y Bodri, 2009269 Y Y U N N U U Y N Y Y N Y Boulet, 2015254 N N U Y Y N Y N U U U Y Y Boulet, 2016277 Y Y N Y Y Y Y U U Y Y Y Y Brinton, 2015136 Y Y N Y U Y Y Y U Y Y Y U Butts, 2014122 Y Y N Y U Y Y Y N Y Y Y Y Chang, 2016276 Y Y N Y Y Y U U U Y Y Y Y Crawford, 2017281 Y Y N Y Y Y Y Y Y Y Y Y Y de Wilde, 2017180 Y Y N Y Y Y U Y Y Y Y Y Y Dhalwani, 2016236 Y Y N Y Y Y Y Y N Y Y Y Y Hershko-Klement, 2016260 U Y U N U U U Y U U U U U Kettner, 2016184 Y Y N Y Y Y Y Y N Y Y Y Y Keyhan, 2018185 Y Y N Y U U Y Y N N Y N Y Kissin, 2015272 Y Y Y Y Y Y Y Y Y Y Y Y Y Knudtson, 2017282 Y Y N Y Y Y Y Y N Y Y Y Y Levi Dunietz, 2017239 Y Y N Y Y Y Y Y Y Y Y Y Y Litzky, 2018284 Y Y N Y U Y Y Y N Y Y Y Y Litzky, 2018290 Y Y N Y U Y Y Y U Y Y Y Y Luke, 2010123 N Y U N N N N N U Y Y U Y Magnusson, 2018287 Y Y N Y U Y Y Y U Y Y Y Y Malchau, 2017186 Y Y N Y U Y Y Y U Y Y Y Y Mancuso, 2016283 Y Y N Y U Y Y U U Y Y Y Y Maxwell, 2008270 N Y N N N U Y N N Y N N N Muller, 2017205 Y Y N N U U U Y U Y Y N Y G-1 Study Nangia, 2011124 U Y U Y N U U N U Y Y Y Y Oyesanya, 2009224 Y Y N N N Y Y Y N Y Y N U Schendelaar, 2011273 Y Y Y Y U U Y Y N Y Y U U Spaan, 2015125 N Y N Y Y Y U Y U Y Y Y U Stewart, 2013203 Y Y N N U Y Y Y U Y Y N Y Tsai, 2011257 N N Y N N U N N N Y Y N Y Verhoeve, 2013249 U U U U U U U U U U U U U Vitek, 2013215 Y Y N Y Y Y Y Y U Y Y Y U Wang, 2017286 Y Y N Y U Y Y Y U Y Y Y Y Williams, 2013213 Y Y N N U Y Y Y U Y Y U Y Williams, 2018289 Y Y N Y U Y Y N U Y Y Y Y Xiong, 2017263 Y Y U Y N U U Y U Y Y Y Y Abbreviations: N=No; U=Unclear; Y=Yes G-2 Figure G-1. 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