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Oruc 2010 (Continued) Interventions L-ornithine L-aspartate: intravenous infusion forty g/day Control: intravenous infusion of placebo (isotonic saline) Duration: 5 days Cointerventions: lactulose and antibiotics Outcomes Outcomes included in meta-analyses: none Country Turkey Neuropsychiatric assessment пїЅ Mental status (West Haven criteria) пїЅ Fasting plasma ammonia пїЅ Critical Flicker Frequency Inclusion period Not described Notes Publication status: abstract Unpublished info: requested however none acquired Risk of bias Bias AuthorsпїЅ judgement Support for judgement Random sequence generation (choice Unclear danger Not described bias) Allocation concealment (choice bias) Unclear risk Not described Blinding of participants and personnel High danger Open trial without blinding of individuals (performance bias) or personnel All outcomes Blinding of outcome evaluation (detection High threat Opentrial without blinding of outcome as- bias) sessors All outcomes Incomplete consequence information (attrition bias) Unclear danger Missing consequence knowledge not described All outcomes Selective reporting (reporting bias) High threat Publication described proportion of par- ticipants who died and proportion with- out improved manifestations of hepatic en- cephalopathy, but it didn't describe num- ber of participantsallocated tointervention and management groups For-pro?t funding Unclear danger Not described Other bias Low risk No different bias identi?ed L-ornithine L-aspartate for prevention and therapy of hepatic encephalopathy in people with cirrhosis (Review) eighty one Copyright пїЅ 2018 The Cochrane Collaboration. 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